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three perform by altering receptor expression with the plasma membrane, by facilitating improvements inside the ligand-binding domain and consequent integrin activation, or by facilitating improvements within the conformation in the transmembrane and intracellular domains of α
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3 and exposing the ligand-binding domain, recognized by the antibody JON/A. These conformational alterations initiated by talin binding also supply a System for protein associations. Whilst Src binding to β
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